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KMID : 1129720060230020105
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Korean Journal of Acupuncture
2006 Volume.23 No. 2 p.105 ~ p.111
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Electroacupuncture suppresses epileptic EEG in experimental induced epileptic rats
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Kim Yun-Jin
Kim Jae-Hyo
Ma Cheng
Shen Mei-Hong
Li Zhong-Ren
Sohn In-Chul
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Abstract
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Objectives: We investigated the effect of electroacupuncture on epileptic rat model and its underlying mechanisms on suppression of the epilepsy.
Methods: It was used pentylenetetrazol induced epileptic rat model and square wave electrical stimulations (5 mA, 5, 40 or 80 Hz frequency) was applied to acupoints on ’Dazhui’ and ’Taichong’ for 30min.
Results: Electroacupuncture suppressed spikes and slow waves of EEG due to the epileptic condition. Out of electroacupuncture, a high frequency of 80Hz had a better effect for suppress epileptic EEG wave.
Conclusions: Electroacupuncture can markedly reduce the excitability of cerebral cortex and strengthen the inhibitory process, checking epilepsy wave. Some intrathalamic nuclei have a promoting or inhibiting effect on epileptic EEG wave. This experimental study we are proposed to Electro-acupuncture can suppression epileptic rat model and it’s scientific mechanisms.
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KEYWORD
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electroacupuncture, epilepsy, electroencephalogram
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